Retinal Hypoxia: Relation to Blood Flow and Oxygen Metabolic Biomarkers
During graded retinal ischemia, we showed a linear relationship between tPO2 both TRBF and DO2. A critical tPO2 value defined the nonlinear biphasic relationships of OEF and MO2 with tPO2. The relationships of these biomarkers show promise for advancing knowledge of retinal ischemia and hypoxia.
Authors
- Sophie Leahy
- Mahnaz Shahidi (ORCID: https://orcid.org/0000-0002-0156-1059)
- Nathanael Matei (ORCID: https://orcid.org/0000-0001-6136-1318)
- Norman P Blair
Institutions
- University of Southern California (US)
- University of Illinois Chicago (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1167/iovs.67.3.32
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness