Arterial Catheter-Associated Proximal Ischemic Injury in Critically Ill Children: Evidence of Endothelial Dysfunction and Immune Dysregulation

In a small pediatric cohort, we identified pathways of immune dysregulation and endothelial dysfunction associated with ACAPII. Because these factors precede ACAPII, there may be a window for treatment.

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Publication Details

Journal
Pediatric Critical Care Medicine
Published
2026-03-13
DOI
https://doi.org/10.1097/pcc.0000000000003943
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Arterial Catheter-Associated Proximal Ischemic Injury in Critically Ill Children: Evidence of Endothelial Dysfunction and Immune Dysregulation

Mark D. Weber, Sarah E. Henrickson, Robert B. Lindell, Teresa Arroyo et al.
Pediatric Critical Care Medicine
Acute Kidney Injury Research
article

Arterial Catheter-Associated Proximal Ischemic Injury in Critically Ill Children: Evidence of Endothelial Dysfunction and Immune Dysregulation

Mark D. Weber, Sarah E. Henrickson, Robert B. Lindell, Teresa Arroyo, Samir Sayed, Hongyan Liu, Amelia Demopoulos, Danielle Traynor, Thomas Conlon, Stephen T. Famularo
article en

Abstract

In a small pediatric cohort, we identified pathways of immune dysregulation and endothelial dysfunction associated with ACAPII. Because these factors precede ACAPII, there may be a window for treatment.

Pediatric Critical Care Medicine
Children's Hospital of Philadelphia (US), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 32%
Acute Kidney Injury Research
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