The deleterous effect of proteinuria in residual kidney function in hemodialysis patients

Nephrotic-range proteinuria at online-HDF initiation is an independent predictor of accelerated RKF loss, including progression to anuria. Its association with elevated β2-microglobulin supports its value as a prognostic marker. Early identification of high-proteinuria patients may enable personalized strategies to preserve RKF and improve outcomes.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2026-03-12
DOI
https://doi.org/10.1093/ndt/gfag058
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
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article

The deleterous effect of proteinuria in residual kidney function in hemodialysis patients

Nuria Rodríguez Mendiola, Beatriz Sánchez Álamo, Irene Minguez, Martha Elisabeth Díaz Domínguez et al.
Nephrology Dialysis Transplantation
Chronic Kidney Disease and Diabetes
article

The deleterous effect of proteinuria in residual kidney function in hemodialysis patients

Nuria Rodríguez Mendiola, Beatriz Sánchez Álamo, Irene Minguez, Martha Elisabeth Díaz Domínguez, Milagros Fernández Lucas
article en

Abstract

Nephrotic-range proteinuria at online-HDF initiation is an independent predictor of accelerated RKF loss, including progression to anuria. Its association with elevated β2-microglobulin supports its value as a prognostic marker. Early identification of high-proteinuria patients may enable personalized strategies to preserve RKF and improve outcomes.

Nephrology Dialysis Transplantation
Universidad de Alcalá (ES), Instituto Cajal (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Hospital Universitario Ramón y Cajal (ES)
Openalex Percentile: Top 32%
Chronic Kidney Disease and Diabetes
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