GLP-1 receptor agonists for weight loss: A systematic review and meta-analysis of randomized controlled trials
GLP-1 receptor agonists significantly increase the likelihood of weight loss versus placebo, with tirzepatide and semaglutide demonstrating the greatest relative efficacy among agents evaluated. These findings support GLP-1-based therapy as an effective component of clinical obesity management.
Authors
- A. AlArjani
- Mohamed Balaha (ORCID: https://orcid.org/0000-0002-0295-4460)
- Abdulelah M. Tawhari
- Abdullah Alahmari
- Abdulaziz Aldosri
- Nehad Ahmad
- Abdulaziz Alruwayyes
Institutions
- Prince Sattam Bin Abdulaziz University (SA)
Publication Details
- Journal
- Medicine
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1097/md.0000000000047994
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00