Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees developed consensus-based imaging recommendations for high-risk neuroblastoma at first presentation and throughout follow-up. These expert opinions aim to improve reproducibility and enhance diagnostic performance in order to advance the current standard of care and assist in the development of future trials.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-03-13
DOI
https://doi.org/10.1002/1545-5017.70180
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Julian M.M. Rogasch, Jürgen F. Schaefer, Hervé J. Brisse, Maria Carmen Garganese et al.
Pediatric Blood & Cancer
Neuroblastoma Research and Treatments
article

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Julian M.M. Rogasch, Jürgen F. Schaefer, Hervé J. Brisse, Maria Carmen Garganese, Pier Luigi Di Paolo, Annemieke Simone Littooij, Catia Olianti, Bart de Keizer, Irmina Sefić Pašić, Hugh Wallace, Simon Wan, Tepas Kapadia
article en

Abstract

Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees developed consensus-based imaging recommendations for high-risk neuroblastoma at first presentation and throughout follow-up. These expert opinions aim to improve reproducibility and enhance diagnostic performance in order to advance the current standard of care and assist in the development of future trials.

Pediatric Blood & Cancer
University College Hospital (GB), NHS Greater Glasgow and Clyde (GB), Royal Hospital for Children (GB), University Medical Center Utrecht (NL), Humboldt-Universität zu Berlin (DE), Azienda Ospedaliero-Universitaria Careggi (IT), Bambino Gesù Children's Hospital (IT), University Children's Hospital Tübingen (DE), Princess Máxima Center (NL), University Clinical Centre Maribor (SI), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Royal Manchester Children's Hospital (GB), University College London (GB), University of Glasgow (GB), Institut Curie (FR)
Openalex Percentile: Top 30%
Neuroblastoma Research and Treatments
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