In Vivo Hyperspectral Imaging of Vasogenic Edema and Cortical Oxygenation in Meningiomas: A Subgroup Interim Analysis of a Prospective Study
PBE in IMs is associated with impaired cortical oxygenation. Larger PBEs paradoxically showed higher StO2, suggesting compensatory mechanisms, while strong tumor enhancement correlated with local hypoxia. These findings suggest that intraoperative HSI may serve as a promising tool for characterizing tumor-brain interactions and support further investigation into PBE pathophysiology.
Authors
- Andreas Melzer (ORCID: https://orcid.org/0000-0002-7874-8946)
- Annekatrin Pfahl (ORCID: https://orcid.org/0000-0002-6285-1586)
- H. Köhler (ORCID: https://orcid.org/0000-0001-9342-3288)
- Ferdinand Weber
- Gizem Zeynep Kurt
- Johannes Wach
- Erdem Güresir
- Martin Vychopen
Institutions
- Bahçeşehir University (TR)
- University of Dundee (GB)
- University Hospital Leipzig (DE)
- Saxon Institute for Applied Biotechnology (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Neurosurgery
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1227/neu.0000000000003991
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00