Instability of Global Burden of Disease Estimates of Deaths and Disability-Adjusted Life-Years From Major Risk Factors
This meta-epidemiological assessment indicates that GBD estimates are substantially unstable, particularly for behavioral risks, making them unlikely to simply reflect genuine changes over time, and warranting caution in interpretation.
Authors
- Emmanuel A. Zavalis (ORCID: https://orcid.org/0000-0001-6205-1362)
- A M Pezzullo
- John P. A. Ioannidis (ORCID: https://orcid.org/0000-0003-3118-6859)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Karolinska Institutet (SE)
- Innovative Research (United States) (US)
- Stanford University (US)
Publication Details
- Journal
- JAMA Health Forum
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1001/jamahealthforum.2026.0108
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00