Methemoglobin and Nitrogen Dioxide Levels During Inhaled Nitric Oxide Therapy at 300 Parts per Million in Healthy Volunteers
Intermittent administration of iNO<sub>300</sub> was safe in healthy adults under real-time monitoring of MetHb and NO<sub>2</sub>. These findings support further clinical investigations into iNO<sub>300</sub> as a potential inhaled therapy for lower respiratory tract infections.
Authors
- Binglan Yu (ORCID: https://orcid.org/0000-0001-5496-2131)
- Edward A. Bittner (ORCID: https://orcid.org/0000-0002-0159-2373)
- Bijan Safaee Fakhr (ORCID: https://orcid.org/0000-0002-2841-1413)
- Carolyn La Vita
- Sara Pidò (ORCID: https://orcid.org/0000-0003-1425-1719)
- Giovanni Bruno (ORCID: https://orcid.org/0000-0003-2900-7196)
- Cristina Mietto (ORCID: https://orcid.org/0000-0001-6626-4699)
- R. Carroll
- H. Wanderley
- Stefano Cenci
- Regina Villalobos
- Run Dong
- Stefano Spina
- Lorenzo Berra
Institutions
- Duke Regional Hospital (US)
- Massachusetts General Hospital (US)
- Politecnico di Milano (IT)
Publication Details
- Journal
- Respiratory Care
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1177/19433654261427690
- Primary Topic
- Methemoglobinemia and Tumor Lysis Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00