Elevated DOCK4 expression correlates with favorable prognosis and immune infiltration in clear cell renal cell carcinoma
DOCK4 is a promising prognostic biomarker in ccRCC, with high expression indicating favorable pathologic staging and improved survival. Its role in modulating the TIME suggests that DOCK4 could also serve as a therapeutic target, potentially guiding future immunotherapy strategies for this aggressive malignancy.
Authors
- J Y Wang
- Fangfang Zhu (ORCID: https://orcid.org/0000-0001-7358-2353)
- Shao-Shuai Hou
- Su-Wei Zhu
- Da-Long He
Institutions
- Shandong Provincial Hospital (CN)
- Tengzhou Central People's Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
- Shandong First Medical University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1080/07853890.2026.2642533
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00