Validation of a novel cognitive-functional outcome measure optimized for early Alzheimer’s Disease: Evidence from the VIVA-MIND trial

Practically significant differences in the efficiency of clinical trials in early AD may be realized by the choice of clinical outcome measure and weighting scheme. Although further verification is needed, we replicate a previous finding that the CFC2 may outperform the CDR-SB in the early AD population.

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Publication Details

Journal
The Journal of Prevention of Alzheimer s Disease
Published
2026-03-13
DOI
https://doi.org/10.1016/j.tjpad.2026.100531
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Validation of a novel cognitive-functional outcome measure optimized for early Alzheimer’s Disease: Evidence from the VIVA-MIND trial

Carolyn Revta, Antje Meyer, Andrew MacKelfresh, Christine Wenzkowski et al.
The Journal of Prevention of Alzheimer s Disease
Dementia and Cognitive Impairment Research
article

Validation of a novel cognitive-functional outcome measure optimized for early Alzheimer’s Disease: Evidence from the VIVA-MIND trial

Carolyn Revta, Antje Meyer, Andrew MacKelfresh, Christine Wenzkowski, Tanja Wassmann, Sylvia Schell-Mader, Jasmin Duehring, Michael Schaeffer, Diane M. Jacobs, Steven D. Edland, Howard H. Feldman, David P. Salmon
article en

Abstract

Practically significant differences in the efficiency of clinical trials in early AD may be realized by the choice of clinical outcome measure and weighting scheme. Although further verification is needed, we replicate a previous finding that the CFC2 may outperform the CDR-SB in the early AD population.

The Journal of Prevention of Alzheimer s DiseaseVol. 13(5)
University of California San Diego (US), Alzheimer’s Disease Neuroimaging Initiative (US)
Openalex Percentile: Top 31%
Dementia and Cognitive Impairment Research
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