Late Venous Thromboembolism Chemoprophylaxis and Increased Risk of Deep Venous Thrombosis, Pulmonary Embolism, and Mortality in Patients with Traumatic Spinal Injury

In this national cohort of traumatic spinal injuries, chemoprophylaxis initiated ≥48 hours after admission was independently associated with increased venous thromboembolism and mortality. These findings support early initiation when clinically feasible while highlighting the need for prospective evaluation of bleeding risk.

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Publication Details

Journal
Journal of the American College of Surgeons
Published
2026-03-13
DOI
https://doi.org/10.1097/xcs.0000000000001917
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

Late Venous Thromboembolism Chemoprophylaxis and Increased Risk of Deep Venous Thrombosis, Pulmonary Embolism, and Mortality in Patients with Traumatic Spinal Injury

Kayla Wilson, Tatiana Cárdenas, Sádia Ali, Michelle Robert et al.
Journal of the American College of Surgeons
Venous Thromboembolism Diagnosis and Management
article

Late Venous Thromboembolism Chemoprophylaxis and Increased Risk of Deep Venous Thrombosis, Pulmonary Embolism, and Mortality in Patients with Traumatic Spinal Injury

Kayla Wilson, Tatiana Cárdenas, Sádia Ali, Michelle Robert, Joseph J. DuBose, Morgan F. Gaither, Sarah McWilliam Schmaltz, Pedro G Teixeira, Karyssa M Nelson, Carlos VR Brown
article en

Abstract

In this national cohort of traumatic spinal injuries, chemoprophylaxis initiated ≥48 hours after admission was independently associated with increased venous thromboembolism and mortality. These findings support early initiation when clinically feasible while highlighting the need for prospective evaluation of bleeding risk.

Journal of the American College of Surgeons
The University of Texas at Austin (US)
Good health and well-being
Openalex Percentile: Top 28%
Venous Thromboembolism Diagnosis and Management
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