A 3D Collagen-Based In Vitro Cancer Model Created Through Modular Tissue Engineering

Our model offers the unique ability to spontaneously reproduce fundamental features of tumours in vitro, capturing the cellular heterogeneity and reprogramming that drive clinical drug resistance.

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Publication Details

Journal
Cancers
Published
2026-03-13
DOI
https://doi.org/10.3390/cancers18060935
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
0.00
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article

A 3D Collagen-Based In Vitro Cancer Model Created Through Modular Tissue Engineering

Mira Bosso, M. Dean Chamberlain, Amelia Gagnon, Breanne Bernice Bevelander et al.
Cancers
Cancer Cells and Metastasis
article

A 3D Collagen-Based In Vitro Cancer Model Created Through Modular Tissue Engineering

Mira Bosso, M. Dean Chamberlain, Amelia Gagnon, Breanne Bernice Bevelander, Rowen Greene, Nima Daneshvar Baghbadorani, Taylor Dzikowski, Morgan Johannson, Parnaz Soori, Mohammadreza Javan
article en

Abstract

Our model offers the unique ability to spontaneously reproduce fundamental features of tumours in vitro, capturing the cellular heterogeneity and reprogramming that drive clinical drug resistance.

CancersVol. 18(6)
University of Saskatchewan (CA), Saskatchewan Cancer Agency (CA)
Good health and well-being
Openalex Percentile: Top 23%
Cancer Cells and Metastasis
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