Single-cell transcriptomics reveals lipid metabolism reprogramming in macrophages in vitro during early stages of Leishmania donovani infection

This study analyzed the host immune response process and the characteristics of parasite-host interactions during L. donovani infection, which may provide a theoretical basis for the development of novel anti-infective treatment strategies in the future.

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Publication Details

Journal
Parasites & Vectors
Published
2026-03-13
DOI
https://doi.org/10.1186/s13071-026-07361-w
Primary Topic
Research on Leishmaniasis Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Single-cell transcriptomics reveals lipid metabolism reprogramming in macrophages in vitro during early stages of Leishmania donovani infection

Zhengjun Yi, Qing Wang, Fei-Ran Li, Bin-Bin Yang et al.
Parasites & Vectors
Research on Leishmaniasis Studies
article

Single-cell transcriptomics reveals lipid metabolism reprogramming in macrophages in vitro during early stages of Leishmania donovani infection

Zhengjun Yi, Qing Wang, Fei-Ran Li, Bin-Bin Yang, Ling-Lin Qu, Zhi-Hui Li, Qi Sun
article en

Abstract

This study analyzed the host immune response process and the characteristics of parasite-host interactions during L. donovani infection, which may provide a theoretical basis for the development of novel anti-infective treatment strategies in the future.

Parasites & Vectors
Weifang Medical University (CN), Harbin Institute of Technology (CN), Heze Municipal Hospital (CN), Shandong Academy of Sciences (CN), Rongcheng City People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 27%
Research on Leishmaniasis Studies
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