Efficient use of the <scp>BioFire® FilmArray®</scp> Meningitis/Encephalitis Panel: a diagnostic stewardship approach
A diagnostic stewardship algorithm employing a WCC threshold of >50 × 10<sup>6</sup>/L for FA/ME testing, with reflex testing of specimens with lower WCC on an alternative viral multiplex PCR, would have reduced annual costs from $23 302 (without stewardship) to $14 646, doubled the positivity rate to 29.54% and detected all clinically significant infections. This study provides insights into optimising FA/ME use in Australia to improve patient management.
Authors
- Katherine A. Bond (ORCID: https://orcid.org/0000-0002-4473-9232)
- Paul Kinsella (ORCID: https://orcid.org/0000-0002-6167-9366)
- Nalian Ibrahim
- E. C. S. Chan (ORCID: https://orcid.org/0000-0001-5443-9201)
- Katie Cronin
Institutions
- The Royal Melbourne Hospital (AU)
- Peter Doherty Institute (AU)
Publication Details
- Journal
- Internal Medicine Journal
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1111/imj.70391
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00