<i>KCNJ5</i> -Negative Primary Aldosteronism: Histopathology and Surgical Outcomes
Nearly half of <i>KCNJ5</i>-negative uPA cases exhibit nonclassical adrenal histopathology, which is associated with significantly lower complete clinical success rates. These findings underscore the prognostic value of histopathologic classification in <i>KCNJ5</i>-negative uPA and support integrating histology and genetics to improve patient management.
Authors
- Ya‐Wen Yang (ORCID: https://orcid.org/0000-0003-0412-584X)
- Peng-Ying Chen
- Yen-Hung Lin
- Che‐Hsiung Wu (ORCID: https://orcid.org/0000-0001-6164-6655)
- Yi‐Yao Chang (ORCID: https://orcid.org/0000-0002-9148-8667)
- Yali Chen (ORCID: https://orcid.org/0000-0001-5396-9307)
- Vin-Cent Wu
- Kang-Yung Peng
- on behalf of the ESUR Prostate MRI Working Group
Institutions
- National Taiwan University (TW)
- Chang Gung University (TW)
- Tzu Chi University (TW)
- Taipei Tzu Chi Hospital (TW)
- National Taiwan University Hospital (TW)
- Buddhist Tzu Chi Medical Foundation (US)
Publication Details
- Journal
- Hypertension
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1161/hypertensionaha.125.26266
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00