Outcomes and management of primary tumors in metastatic MSI/dMMR colorectal cancer patients treated with immune checkpoint inhibitors: a cohort study

If PT is left in place at ICI initiation, close monitoring is required due to its specific evolution. Resection may be indicated for symptomatic stenosis. Prospective trials are needed to define the role of endoscopic monitoring and indication of PT resection in first-line ICI.

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Publication Details

Journal
ESMO Gastrointestinal Oncology
Published
2026-03-14
DOI
https://doi.org/10.1016/j.esmogo.2026.100319
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes and management of primary tumors in metastatic MSI/dMMR colorectal cancer patients treated with immune checkpoint inhibitors: a cohort study

C. Grosnon, L. Mas, J. Lefèvre, R. Cohen et al.
ESMO Gastrointestinal Oncology
Multiple and Secondary Primary Cancers
article

Outcomes and management of primary tumors in metastatic MSI/dMMR colorectal cancer patients treated with immune checkpoint inhibitors: a cohort study

C. Grosnon, L. Mas, J. Lefèvre, R. Cohen, T. Samaille, A. Dardenne, Y. Parc, T. André
article en

Abstract

If PT is left in place at ICI initiation, close monitoring is required due to its specific evolution. Resection may be indicated for symptomatic stenosis. Prospective trials are needed to define the role of endoscopic monitoring and indication of PT resection in first-line ICI.

ESMO Gastrointestinal OncologyVol. 12
Inserm (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Saint-Antoine (FR), Centre de Recherche Saint-Antoine (FR)
Good health and well-being
Openalex Percentile: Top 25%
Multiple and Secondary Primary Cancers
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