EXPRESS: Consensus co-expression analysis identifies a common set of co-expressed genes associated with diabetic peripheral neuropathy and chemotherapy-induced peripheral neuropathy
Our analysis reveals a convergent molecular signature underlying both DPN and CIPN, centered on metabolic reprogramming, transcriptional stress, and programmed cell death. These findings provide a systems-level framework for developing therapies targeting shared pathological mechanisms.
Authors
- Nam Woo Cho (ORCID: https://orcid.org/0000-0002-5785-9698)
- Kord M. Kober (ORCID: https://orcid.org/0000-0001-9732-3321)
- Alexandre Chan (ORCID: https://orcid.org/0000-0003-4391-4219)
- Marina Sirota (ORCID: https://orcid.org/0000-0002-7246-6083)
- Esther Chavez-Iglesias (ORCID: https://orcid.org/0009-0004-7306-3544)
- A. B. Olshen
- Niharika Dixit
- Sue Yom
Institutions
- University of California, San Francisco (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
Publication Details
- Journal
- Molecular Pain
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1177/17448069261435315
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00