Clinical and immunologic status of a child conceived following maternal administration of CD19 CAR T-cells for systemic lupus erythematosus
This case represents the earliest reported pregnancy following CD19 CAR-T therapy for SLE and the first to include neonatal immune assessment at birth. No evidence of transplacental CAR-T transfer or clinically significant neonatal immunodeficiency was observed. Additional cases and long-term follow-up are required to guide reproductive counseling after CAR-T therapy.
Authors
- Elliot D. Rosenstein (ORCID: https://orcid.org/0000-0001-7681-4615)
- Mohammad Cherry
- Neil Kramer
Institutions
- Overlook Medical Center (US)
- Atlantic Health System (US)
Publication Details
- Journal
- Clinical and Experimental Rheumatology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.55563/clinexprheumatol/g0ehvq
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00