Bleeding rates, healthcare utilization, and costs among patients with hemophilia a without inhibitors treated with concomitant octocog alfa or extended half-life factor VIII while on emicizumab prophylaxis

While the choice of concomitant FVIII does not substantially influence ABR<sub>b</sub> or bleed-related HCRU, significantly lower pharmacy costs with octocog alfa compared with EHL agents highlight its potential cost saving and support its consideration as a preferred on-demand treatment option in patients with HA without inhibitors on emicizumab prophylaxis.

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Publication Details

Journal
Journal of Medical Economics
Published
2026-03-13
DOI
https://doi.org/10.1080/13696998.2026.2642552
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Bleeding rates, healthcare utilization, and costs among patients with hemophilia a without inhibitors treated with concomitant octocog alfa or extended half-life factor VIII while on emicizumab prophylaxis

Caitlin Montcrieff, Jorge Caicedo, Ekaterina Ponomareva, Michael Bullano et al.
Journal of Medical Economics
Hemophilia Treatment and Research
article

Bleeding rates, healthcare utilization, and costs among patients with hemophilia a without inhibitors treated with concomitant octocog alfa or extended half-life factor VIII while on emicizumab prophylaxis

Caitlin Montcrieff, Jorge Caicedo, Ekaterina Ponomareva, Michael Bullano, Alicia Cerretani, Angela (Qi) Fan
article en

Abstract

While the choice of concomitant FVIII does not substantially influence ABR<sub>b</sub> or bleed-related HCRU, significantly lower pharmacy costs with octocog alfa compared with EHL agents highlight its potential cost saving and support its consideration as a preferred on-demand treatment option in patients with HA without inhibitors on emicizumab prophylaxis.

Journal of Medical EconomicsVol. 29(1)
Takeda (United States) (US), Takeda (Japan) (JP), CytRx (United States) (US)
Openalex Percentile: Top 22%
Hemophilia Treatment and Research
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