Bleeding rates, healthcare utilization, and costs among patients with hemophilia a without inhibitors treated with concomitant octocog alfa or extended half-life factor VIII while on emicizumab prophylaxis
While the choice of concomitant FVIII does not substantially influence ABR<sub>b</sub> or bleed-related HCRU, significantly lower pharmacy costs with octocog alfa compared with EHL agents highlight its potential cost saving and support its consideration as a preferred on-demand treatment option in patients with HA without inhibitors on emicizumab prophylaxis.
Authors
- Caitlin Montcrieff (ORCID: https://orcid.org/0000-0002-3540-9426)
- Jorge Caicedo
- Ekaterina Ponomareva (ORCID: https://orcid.org/0000-0002-6334-8034)
- Michael Bullano (ORCID: https://orcid.org/0000-0002-9961-4576)
- Alicia Cerretani
- Angela (Qi) Fan
Institutions
- Takeda (United States) (US)
- Takeda (Japan) (JP)
- CytRx (United States) (US)
Publication Details
- Journal
- Journal of Medical Economics
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1080/13696998.2026.2642552
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00