Clinical features of androgen abuse withdrawal in men during the first year of cessation: a community dwelling study

Among men in the first year after stopping androgen abuse, psychological symptoms and reduced quality-of-life were most strongly associated with psychiatric comorbidity than biochemical recovery. These findings challenge the assumption that androgen withdrawal symptoms are predominantly driven by hypogonadism, and supports developing psychological and behavioural interventions, rather than pharmacological, to support androgen withdrawal in men.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2026-03-11
DOI
https://doi.org/10.1210/clinem/dgag110
Citations
1
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
30.73
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article

Clinical features of androgen abuse withdrawal in men during the first year of cessation: a community dwelling study

Joseph Kean, Paul Bassett, Nipun Lakshitha de Silva, Waljit S. Dhillo et al.
1 citations
The Journal of Clinical Endocrinology & Metabolism
Hormonal and reproductive studies
30.73
article

Clinical features of androgen abuse withdrawal in men during the first year of cessation: a community dwelling study

Joseph Kean, Paul Bassett, Nipun Lakshitha de Silva, Waljit S. Dhillo, Channa Nalin Jayasena, Bonnie Grant, Anne Lingford-Hughes, Kim Wolff, Rodrigo Aguilera, Oliver C B Quinton, Maha Gumssani
article en
1 citations

Abstract

Among men in the first year after stopping androgen abuse, psychological symptoms and reduced quality-of-life were most strongly associated with psychiatric comorbidity than biochemical recovery. These findings challenge the assumption that androgen withdrawal symptoms are predominantly driven by hypogonadism, and supports developing psychological and behavioural interventions, rather than pharmacological, to support androgen withdrawal in men.

The Journal of Clinical Endocrinology & Metabolism
King's College London (GB), General Sir John Kotelawala Defence University (LK), Bloodworks Northwest (US), Amersham Hospital (GB), Imperial College London (GB)
Openalex Percentile: Top 0%
Hormonal and reproductive studies
30.73
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