Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury
TMP alleviates CI/RI by promoting mitophagy through the YAP/Parkin signaling pathway, suggesting mitophagy modulation as a potential therapeutic strategy for ischemic brain injury.
Authors
- M. Wang
- Weiru Jiang
- Jiadong Xu (ORCID: https://orcid.org/0009-0005-0463-9199)
- Yan Feng (ORCID: https://orcid.org/0000-0001-6890-7053)
- Liang Xu (ORCID: https://orcid.org/0000-0002-2700-4840)
- Sihan Wang (ORCID: https://orcid.org/0000-0002-3481-9167)
- Yan Fang (ORCID: https://orcid.org/0000-0001-9645-3888)
- Yani Zhang (ORCID: https://orcid.org/0009-0007-8769-8518)
- Lisheng Chu
- Yihan Qian
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Biomolecules
- Published
- 2026-03-13
- DOI
- https://doi.org/10.3390/biom16030429
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00