Short bowel syndrome-associated intestinal failure: diagnosis and prognosis

Short bowel syndrome in adults is a clinical malabsorptive syndrome associated with having <200 cm of residual small bowel in continuity, measured from the duodenojejunal flexure. Intestinal failure is the reduction of gut function below the minimum required for the absorption of macronutrients and/or water and electrolytes, thereby requiring parenteral support to maintain health and/or growth. The remaining small bowel length and segment, and health of the remnant bowel have important prognostic implications. Care gaps exist regarding the diagnosis and management of this condition and future efforts should address these disparities in order to provide optimal care to these patients.

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Publication Details

Journal
Expert Review of Gastroenterology & Hepatology
Published
2026-03-13
DOI
https://doi.org/10.1080/17474124.2026.2646296
Primary Topic
Clinical Nutrition and Gastroenterology
Type
article
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article

Short bowel syndrome-associated intestinal failure: diagnosis and prognosis

John K DiBaise
Expert Review of Gastroenterology & Hepatology
Clinical Nutrition and Gastroenterology
article

Short bowel syndrome-associated intestinal failure: diagnosis and prognosis

John K DiBaise
article en

Abstract

Short bowel syndrome in adults is a clinical malabsorptive syndrome associated with having <200 cm of residual small bowel in continuity, measured from the duodenojejunal flexure. Intestinal failure is the reduction of gut function below the minimum required for the absorption of macronutrients and/or water and electrolytes, thereby requiring parenteral support to maintain health and/or growth. The remaining small bowel length and segment, and health of the remnant bowel have important prognostic implications. Care gaps exist regarding the diagnosis and management of this condition and future efforts should address these disparities in order to provide optimal care to these patients.

Expert Review of Gastroenterology & Hepatology
WinnMed (US)
Openalex Percentile: Top 23%
Clinical Nutrition and Gastroenterology
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