Arthrospira platensis prevents impairment of intestinal smooth muscle relaxation in diet-induced obesity via modulation of nitric oxide, prostanoid and oxidative stress pathways
These findings provide mechanistic support for the traditional use of A. platensis, demonstrating that its protective effects on intestinal smooth muscle function are mediated by the modulation of convergent inflammatory and redox pathways. The results highlight A. platensis as an ethnopharmacologically relevant natural product with potential for preventing obesity-associated gastrointestinal dysmotility.
Authors
- Ulrich Vasconcelos da Rocha Gomes
- Ray Ravilly Alves Arruda (ORCID: https://orcid.org/0000-0002-7591-9703)
- Brena Freire de Oliveira Claudino
- Anderson Fellyp Avelino Diniz (ORCID: https://orcid.org/0000-0002-9659-1495)
- Maxsyara Felismino da Silva Soares
- Michel Benício De Melo (ORCID: https://orcid.org/0009-0004-4778-0515)
- José Edvaldo Cavalcanti de Sousa Filho
- Bárbara Cavalcanti Barros
- Bagnólia Araújo da Silva
- João Marcos Araújo da Silva
Institutions
- Universidade Federal da Paraíba (BR)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1016/j.jep.2026.121507
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00