Management of pediatric patients with moyamoya arteriopathy and middle aortic syndrome: a retrospective single-institution case series

Managing comorbid moyamoya arteriopathy and MAS is challenging, as patients have a higher risk of ischemic perioperative complications. These patients may have hypertension secondary to their aortic disease, and treating the aortic disease may correct the hypertension but with possible new relative hypotension and relative cerebral hypoperfusion. Consequently, moyamoya revascularization prior to aortic repair may be a strategy to reduce the risk of stroke.

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Publication Details

Journal
Journal of Neurosurgery Pediatrics
Published
2026-03-13
DOI
https://doi.org/10.3171/2025.11.peds25460
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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article

Management of pediatric patients with moyamoya arteriopathy and middle aortic syndrome: a retrospective single-institution case series

Alfred P. See, Carolina Lopes, Craig D. McClain, Soliman Oushy et al.
Journal of Neurosurgery Pediatrics
Moyamoya disease diagnosis and treatment
article

Management of pediatric patients with moyamoya arteriopathy and middle aortic syndrome: a retrospective single-institution case series

Alfred P. See, Carolina Lopes, Craig D. McClain, Soliman Oushy, Laura L. Lehman, Deborah R. Stein, Michael A. Ferguson, Jennifer Judge, J Rispoli, Edward R. Smith, Darren B. Orbach, Michelle Dowling
article en

Abstract

Managing comorbid moyamoya arteriopathy and MAS is challenging, as patients have a higher risk of ischemic perioperative complications. These patients may have hypertension secondary to their aortic disease, and treating the aortic disease may correct the hypertension but with possible new relative hypotension and relative cerebral hypoperfusion. Consequently, moyamoya revascularization prior to aortic repair may be a strategy to reduce the risk of stroke.

Journal of Neurosurgery Pediatrics
Boston Children's Hospital (US), Harvard University (US), Center for Pain and the Brain (US)
Good health and well-being
Openalex Percentile: Top 22%
Moyamoya disease diagnosis and treatment
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