Granulocyte-macrophage colony-stimulating factor at work: Promoting vascular maturation for accelerated wound healing
GM-CSF promotes PECAM1 expression, angiogenesis, and vascular maturation in ECs by upregulating VEGF and Ang-1 in PCs. These effects enhance the interaction between endothelial cells and pericytes, thereby contributing to vascular stabilization and improved wound healing.
Authors
- Haijun Cai
- Wenjie Ying
- Pengyu Sun
- Shuangshuang Wang
- Jianhai Chen
Institutions
- Taizhou First People's Hospital (CN)
- The First People's Hospital of Wenling (CN)
Publication Details
- Journal
- Molecular and Cellular Probes
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1016/j.mcp.2026.102069
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00