Sex-related and age-related differences in healthcare use before multiple sclerosis symptom onset: a matched cohort study
Sex-specific and age-specific differences in physician visits extended up to 15 years pre-MS onset, suggesting a durable prodromal signature, most evident in females and those aged 30-49 years.
Authors
- Yinshan Zhao (ORCID: https://orcid.org/0000-0003-1924-9378)
- Farahnaz Amini (ORCID: https://orcid.org/0000-0002-9491-0851)
- Marta Ruiz-Algueró
- Helen Tremlett
- Ruth Ann Marrie
- Feng Zhu
Institutions
- Dalhousie University (CA)
- University of British Columbia (CA)
- Nova Scotia Health Authority (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1136/jnnp-2025-338045
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Committee for Treatment and Research in Multiple Sclerosis
- Multiple Sclerosis Scientific Research Foundation
- European Genomic Institute for Diabetes
- Multiple Sclerosis Society
- Dalhousie University
- Canadian Institutes of Health Research