<i>Candida auris</i> metabolism and growth preferences in physiologically relevant skin-like conditions
<i>Candida auris</i> is an emerging fungal pathogen with human skin as its primary site of colonization and subsequent transmission. Here, we show the importance of conventional and alternative carbon metabolism for the ability of <i>C. auris</i> to grow in artificial skin-like media. This knowledge provides a better understanding of <i>C. auris</i> metabolism and sheds light on genes and pathways that could be targeted to interfere with persistent skin colonization.
Authors
- Clay Deming (ORCID: https://orcid.org/0000-0002-7745-1518)
- Zeyang Shen (ORCID: https://orcid.org/0000-0003-3870-1390)
- Ryan A. Blaustein (ORCID: https://orcid.org/0000-0001-8879-7453)
- Sean Conlan (ORCID: https://orcid.org/0000-0001-6848-3465)
- Jonathan P. Nicklas (ORCID: https://orcid.org/0000-0003-2320-0497)
- Julia A. Segre (ORCID: https://orcid.org/0000-0001-6860-348X)
- ShihQueen Lee-Lin
Institutions
- Georgetown University (US)
- National Human Genome Research Institute (US)
- University of Maryland, College Park (US)
- Washington State University (US)
Publication Details
- Journal
- mBio
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1128/mbio.03117-25
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00