Late-life body mass index and Alzheimer disease conversion in mild cognitive impairment: Nonlinear risk and structural MRI correlates
Baseline BMI captures prognostic heterogeneity in MCI and is accompanied by differential baseline neurodegeneration. Short-term weight change and amyloid status did not materially refine the BMI-group association. The transition point warrants external validation.
Authors
- Yu Hou
- Huaqing Chu
- Runzhi Zhao
- Zhichao Li (ORCID: https://orcid.org/0000-0002-5105-3570)
- Qi Hou
- Qing Xu
- Shuai Li
- Hui Zheng
- Xiyuan Xu
- Jie Yu
- Linhui Ma
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- Archives of Gerontology and Geriatrics
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1016/j.archger.2026.106217
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00