Local Control of Bladder/Prostate Rhabdomyosarcoma: An Expert Consensus Guideline From the International Soft Tissue Sarcoma Consortium (INSTRuCT)

The local treatment of bladder and prostate rhabdomyosarcoma is a multidisciplinary decision, incorporating elements of patient age, tumor size and location, nodal involvement, and access to local expertise and technology. The relative absence of long-term bladder and bowel function outcome data complicates discussions, particularly given improved survival rates and development of new surgical and radiotherapy techniques. These INSTRuCT guidelines, a collaboration of the Children's Oncology Group, Soft Tissue Sarcoma Committee, European Pediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe, reflect international expert consensus and are intended to inform practice, generate discussion, and highlight areas of future inquiry.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-03-13
DOI
https://doi.org/10.1002/1545-5017.70183
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Local Control of Bladder/Prostate Rhabdomyosarcoma: An Expert Consensus Guideline From the International Soft Tissue Sarcoma Consortium (INSTRuCT)

Beate Timmerman, S. Perkins, Daniel J. Indelicato, Naima Smeulders et al.
Pediatric Blood & Cancer
Sarcoma Diagnosis and Treatment
article

Local Control of Bladder/Prostate Rhabdomyosarcoma: An Expert Consensus Guideline From the International Soft Tissue Sarcoma Consortium (INSTRuCT)

Beate Timmerman, S. Perkins, Daniel J. Indelicato, Naima Smeulders, Cyrus Chargari, Hélène Martelli, Candace F. Granberg, Amanda F Buchanan, Niccolò Passoni, Raquel Davila Fajardo, Jonathan C. Routh, Joerg Fuchs
article en

Abstract

The local treatment of bladder and prostate rhabdomyosarcoma is a multidisciplinary decision, incorporating elements of patient age, tumor size and location, nodal involvement, and access to local expertise and technology. The relative absence of long-term bladder and bowel function outcome data complicates discussions, particularly given improved survival rates and development of new surgical and radiotherapy techniques. These INSTRuCT guidelines, a collaboration of the Children's Oncology Group, Soft Tissue Sarcoma Committee, European Pediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe, reflect international expert consensus and are intended to inform practice, generate discussion, and highlight areas of future inquiry.

Pediatric Blood & Cancer
Mayo Clinic (US), University of Kentucky (US), Duke University (US), Washington University in St. Louis (US), Great Ormond Street Hospital for Children NHS Foundation Trust (GB), Institut Gustave Roussy (FR), University Medical Center Utrecht (NL), University of Florida (US), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Pitié-Salpêtrière Hospital (FR), University Children's Hospital Tübingen (DE), Princess Máxima Center (NL), Texas Children's Hospital (US), West German Heart and Vascular Center Essen (DE), Bicêtre Hospital (FR), The University of Texas Southwestern Medical Center (US), Florida College (US)
Partnerships for the goals
Openalex Percentile: Top 23%
Sarcoma Diagnosis and Treatment
DOISourceOpenAlex
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