MiR‐10a‐5p aggravates podocyte injury in diabetic nephropathy by inhibiting E2f7‐mediated autophagy

This study identifies the miR-10a-5p/E2f7 axis as a critical regulator of podocyte injury and autophagy in DN. Therapeutic inhibition of miR-10a-5p may represent a promising strategy for preserving podocyte function and attenuating DN injury.

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Publication Details

Journal
Diabetic Medicine
Published
2026-03-12
DOI
https://doi.org/10.1111/dme.70270
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

MiR‐10a‐5p aggravates podocyte injury in diabetic nephropathy by inhibiting E2f7‐mediated autophagy

Wulin Tong, Ting Liu
Diabetic Medicine
Autophagy in Disease and Therapy
article

MiR‐10a‐5p aggravates podocyte injury in diabetic nephropathy by inhibiting E2f7‐mediated autophagy

Wulin Tong, Ting Liu
article en

Abstract

This study identifies the miR-10a-5p/E2f7 axis as a critical regulator of podocyte injury and autophagy in DN. Therapeutic inhibition of miR-10a-5p may represent a promising strategy for preserving podocyte function and attenuating DN injury.

Diabetic Medicine
Hangzhou Hospital of Traditional Chinese Medicine (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Openalex Percentile: Top 25%
Autophagy in Disease and Therapy
DOISourceOpenAlex
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