Prebiotic Modulation of FMT Donor Microbiota Enhances MASLD-Relevant Taxa and Functions in an In Vitro Gut Model

These findings suggest that prebiotic supplementation can selectively enrich MASLD-relevant microbial taxa and functions in donor-derived FMT material, supporting their potential as adjuvants to enhance the efficacy and disease-specificity of FMT interventions for MASLD.

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Publication Details

Journal
Journal of Applied Microbiology
Published
2026-03-12
DOI
https://doi.org/10.1093/jambio/lxag074
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
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article

Prebiotic Modulation of FMT Donor Microbiota Enhances MASLD-Relevant Taxa and Functions in an In Vitro Gut Model

G. D. F. Reid, Seema Nair Parvathy, Kait F. Al, Jeremy P. Burton et al.
Journal of Applied Microbiology
Gut microbiota and health
article

Prebiotic Modulation of FMT Donor Microbiota Enhances MASLD-Relevant Taxa and Functions in an In Vitro Gut Model

G. D. F. Reid, Seema Nair Parvathy, Kait F. Al, Jeremy P. Burton, Suyang Jia, Michael Silverman
article en

Abstract

These findings suggest that prebiotic supplementation can selectively enrich MASLD-relevant microbial taxa and functions in donor-derived FMT material, supporting their potential as adjuvants to enhance the efficacy and disease-specificity of FMT interventions for MASLD.

Journal of Applied Microbiology
Western University (CA), Lawson Health Research Institute (CA)
Zero hunger
Openalex Percentile: Top 23%
Gut microbiota and health
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