Parathyroid Carcinoma Mimicking Thyroid Hyalinizing Trabecular Tumor: A Case Report and Review of Atypical Presentations of Parathyroid Carcinoma

We present a parathyroid carcinoma with hyalinizing trabecular architecture and a prominent spindle-cell component. The tumor closely mimicked a hyalinizing trabecular tumor of the thyroid due to its trabecular growth, eosinophilic hyalinized stroma, and nuclear features including grooves and intranuclear pseudoinclusions. Recognition of this rare pattern is important to avoid misclassification.

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Publication Details

Journal
International Journal of Surgical Pathology
Published
2026-03-13
DOI
https://doi.org/10.1177/10668969261422690
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Parathyroid Carcinoma Mimicking Thyroid Hyalinizing Trabecular Tumor: A Case Report and Review of Atypical Presentations of Parathyroid Carcinoma

S N I S H I I A L, Scott M. Wilhelm, Myriam Decaussin-Petrucci, Paola Loreto-Palacio
International Journal of Surgical Pathology
Parathyroid Disorders and Treatments
article

Parathyroid Carcinoma Mimicking Thyroid Hyalinizing Trabecular Tumor: A Case Report and Review of Atypical Presentations of Parathyroid Carcinoma

S N I S H I I A L, Scott M. Wilhelm, Myriam Decaussin-Petrucci, Paola Loreto-Palacio
article en

Abstract

We present a parathyroid carcinoma with hyalinizing trabecular architecture and a prominent spindle-cell component. The tumor closely mimicked a hyalinizing trabecular tumor of the thyroid due to its trabecular growth, eosinophilic hyalinized stroma, and nuclear features including grooves and intranuclear pseudoinclusions. Recognition of this rare pattern is important to avoid misclassification.

International Journal of Surgical Pathology
Université Claude Bernard Lyon 1 (FR), Lyon College (US), University Hospitals of Cleveland (US), Case Western Reserve University (US)
Openalex Percentile: Top 32%
Parathyroid Disorders and Treatments
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