The longitudinal and reversible causal link between depressive symptoms and cardiovascular disease among middle-aged and older adults: findings from three national cohorts
This multi-cohort study provides evidence for a longitudinal causal relationship between depressive symptoms and CVD, showing temporal cumulative effect and a risk pattern consistent with reversible association. These results highlight the need to integrate mental health care into CVD prevention.
Authors
- Yong Ge
- Teng Sun (ORCID: https://orcid.org/0009-0008-1205-1426)
- Dong Shen (ORCID: https://orcid.org/0000-0003-1907-9890)
- Shoujie Feng
- Cheng Zhang
- Hao Zhang
- Shuyuan Li
- Hongjiang Liu
- Xiang Tang
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Psychiatry Research
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1016/j.psychres.2026.117095
- Primary Topic
- Cardiac Health and Mental Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00