Enhanced tumor retention of the novel LAT1-targeting PET probe [18F]FAMT-OMe: A comparative study with [18F]FAMT in glioma mouse models
[<sup>18</sup>F]FAMT-OMe showed improved tumor retention on PET compared with [<sup>18</sup>F]FAMT in the C6 glioma tumor model, suggesting its potential utility for future applications in LAT1-targeted PET.
Authors
- Kenta Kurimoto
- Mitsunori Kirihata (ORCID: https://orcid.org/0000-0002-4183-9107)
- Kayako Isohashi (ORCID: https://orcid.org/0000-0002-2081-3020)
- Takanori Kobayashi (ORCID: https://orcid.org/0000-0001-7118-6955)
- Thosapol Sampunta
- Yoshikatsu Kanai (ORCID: https://orcid.org/0000-0001-8126-286X)
- Sadahiro Naka
- Kazuko Kaneda-Nakashima
- Yoichiro Ohta
- Tadashi Watabe
- Noriyuki Tomiyama
- Mitsuaki Tatsumi
- Hiroki Kato
Institutions
- Osaka City University (JP)
- Osaka University Hospital (JP)
- Tokyo Metropolitan University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Nuclear Medicine and Biology
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1016/j.nucmedbio.2026.109623
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00