Impact of Laterality on Inpatient Outcomes and Complications of Middle Cerebral Artery Acute Ischemic Stroke

Patients with R-MCAS were more likely to receive endovascular thrombectomy and less likely to receive intravascular thrombolysis. R-MCASs were also associated with worse discharge disposition and increased likelihood of inpatient mortality. The National Institutes of Health Stroke Scale bias toward assessment and valuation of patients' language abilities may place patients with R-MCAS at increased risk of adverse poststroke outcomes and complications. Recognition of the subtle signs of nondominant hemisphere strokes may lead to more rapid detection, effective treatment, and improved outcomes.

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Publication Details

Journal
Stroke
Published
2026-03-13
DOI
https://doi.org/10.1161/strokeaha.125.053378
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of Laterality on Inpatient Outcomes and Complications of Middle Cerebral Artery Acute Ischemic Stroke

Stephan A. Mayer, Nabeel R Ahmed, Aryan Malhotra, Ariel Sacknovitz et al.
Stroke
Acute Ischemic Stroke Management
article

Impact of Laterality on Inpatient Outcomes and Complications of Middle Cerebral Artery Acute Ischemic Stroke

Stephan A. Mayer, Nabeel R Ahmed, Aryan Malhotra, Ariel Sacknovitz, S. Albert, Chaitanya Medicherla, Aarti Kishore Jain, Austin B. Carpenter, Zehra Uysal, Fawaz Al-Mufti, Nimrod Gozum, Gurmeen Kaur, Ji Chong, Chirag D. Gandhi
article en

Abstract

Patients with R-MCAS were more likely to receive endovascular thrombectomy and less likely to receive intravascular thrombolysis. R-MCASs were also associated with worse discharge disposition and increased likelihood of inpatient mortality. The National Institutes of Health Stroke Scale bias toward assessment and valuation of patients' language abilities may place patients with R-MCAS at increased risk of adverse poststroke outcomes and complications. Recognition of the subtle signs of nondominant hemisphere strokes may lead to more rapid detection, effective treatment, and improved outcomes.

Stroke
Westchester Medical Center (US), Anna Needs Neuroblastoma Answers (US)
Good health and well-being
Openalex Percentile: Top 25%
Acute Ischemic Stroke Management
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