Potential of the signature index (S-index), a diffusion MRI Biomarker, to enhance diagnosis of clinically significant prostate cancer and decrease the rate of unnecessary biopsies

The S-index and other diffusion MRI biomarkers demonstrate strong performance for the classification of clinically significant prostate cancer and may represent an important step toward enhancing the clinical value of MRI for improving prostate cancer management.

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Publication Details

Journal
European Journal of Radiology
Published
2026-03-14
DOI
https://doi.org/10.1016/j.ejrad.2026.112788
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Potential of the signature index (S-index), a diffusion MRI Biomarker, to enhance diagnosis of clinically significant prostate cancer and decrease the rate of unnecessary biopsies

Pornphan Wibulpolprasert, Kittinut Kijvikai, Sith Phongkitkarun, Suchin Worawichawong et al.
European Journal of Radiology
Prostate Cancer Diagnosis and Treatment
article

Potential of the signature index (S-index), a diffusion MRI Biomarker, to enhance diagnosis of clinically significant prostate cancer and decrease the rate of unnecessary biopsies

Pornphan Wibulpolprasert, Kittinut Kijvikai, Sith Phongkitkarun, Suchin Worawichawong, Pattarasuda Leelarujijaroen, Adun Kampaengtip, Denis Le Bihan
article en

Abstract

The S-index and other diffusion MRI biomarkers demonstrate strong performance for the classification of clinically significant prostate cancer and may represent an important step toward enhancing the clinical value of MRI for improving prostate cancer management.

European Journal of RadiologyVol. 199
Mahidol University (TH), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Université Paris-Saclay (FR), CEA Paris-Saclay - Etablissement de Saclay (FR), CEA Paris-Saclay (FR), Ramathibodi Hospital (TH)
Good health and well-being
Openalex Percentile: Top 23%
Prostate Cancer Diagnosis and Treatment
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Potential of the signature index (S-index), a diffusion MRI Biomarker, to enhance diagnosis of clinically significant prostate cancer and decrease the rate of unnecessary biopsies — Pornphan Wibulpolprasert, Kittinut Kijvikai, et al. · European Journal of Radiology (2026) | TGRS Research Map | TGRS