Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer
Circulating Musclin may reveal information on skeletal muscle integrity and subclinical cardiac dysfunction, identifying cancer patients at increased functional and prognostic risk. These findings support Musclin as a biologically plausible and clinically relevant biomarker at the interface of muscle-heart signalling.
Authors
- Daniel Finke (ORCID: https://orcid.org/0000-0002-0536-7536)
- Jannek Brauer
- Joerg Heineke (ORCID: https://orcid.org/0000-0002-1541-3030)
- Sebastian Welf Romann (ORCID: https://orcid.org/0000-0002-4569-8604)
- Norbert Frey
- Lorenz H. Lehmann
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- German Centre for Cardiovascular Research (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1111/bph.70404
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00