Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 367 988 people using natural language processing
CCD and atrophy have implications for future disease risk and can be identified at scale using NLP of clinical reports. Prevention of neurological disease in people with CCD should be a priority for healthcare policy makers.
Authors
- Laura Sherlock (ORCID: https://orcid.org/0000-0002-1732-9713)
- David M. Kent (ORCID: https://orcid.org/0000-0002-9205-5070)
- Emily Ball (ORCID: https://orcid.org/0000-0002-7445-9581)
- B. Alex
- Michael T. C. Poon (ORCID: https://orcid.org/0000-0002-0053-2184)
- William Whiteley (ORCID: https://orcid.org/0000-0002-4816-8991)
- Richard Tobin (ORCID: https://orcid.org/0000-0003-4050-7888)
- Mome Mukherjee (ORCID: https://orcid.org/0000-0002-3083-436X)
- Emma Davidson (ORCID: https://orcid.org/0000-0002-5182-8495)
- Heather C. Whalley (ORCID: https://orcid.org/0000-0002-4505-8869)
- Alice Hosking (ORCID: https://orcid.org/0000-0001-6900-7778)
- He Zhang (ORCID: https://orcid.org/0000-0002-0184-9319)
- Claire Grover (ORCID: https://orcid.org/0000-0001-7019-1250)
- Grant Mair
- Joanna M Wardlaw
- Matthew Henry Iveson
Institutions
- Tufts University (US)
- British Heart Foundation (GB)
- University of Oxford (GB)
- UK Dementia Research Institute (GB)
- Health Data Research UK (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1136/jnnp-2025-337689
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- NHS Health Scotland
- Alan Turing Institute
- Alzheimer's Society
- National Institute for Health and Care Research
- Edith Murphy Foundation
- Medical Research Council