Latest developments in urinary tumor DNA and its current clinical role in urothelial bladder cancer and upper tract urothelial carcinoma

There is accumulating evidence on the potential use of utDNA for the diagnosis of urothelial carcinoma in the bladder as well as in the upper tract, while preliminary studies show promising results with sensitivities around 80-90% and specificities 90-100%, further research is needed.

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Publication Details

Journal
Current Opinion in Urology
Published
2026-03-04
DOI
https://doi.org/10.1097/mou.0000000000001373
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Latest developments in urinary tumor DNA and its current clinical role in urothelial bladder cancer and upper tract urothelial carcinoma

Daniel Sánchez-Zalabardo, Daniel A. González-Padilla, Felipe Villacampa-Aubá, Félix Guerrero-Ramos et al.
Current Opinion in Urology
Bladder and Urothelial Cancer Treatments
article

Latest developments in urinary tumor DNA and its current clinical role in urothelial bladder cancer and upper tract urothelial carcinoma

Daniel Sánchez-Zalabardo, Daniel A. González-Padilla, Felipe Villacampa-Aubá, Félix Guerrero-Ramos, José Daniel Subiela, Renate Pichler
article en

Abstract

There is accumulating evidence on the potential use of utDNA for the diagnosis of urothelial carcinoma in the bladder as well as in the upper tract, while preliminary studies show promising results with sensitivities around 80-90% and specificities 90-100%, further research is needed.

Current Opinion in Urology
Universidad de Alcalá (ES), Universität Innsbruck (AT), Hospital Universitario 12 De Octubre (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Restaurant Opportunities Centers United (US), Clinica Universidad de Navarra (ES), Hospital Universitario HM Sanchinarro (ES), Hospital Universitario Ramón y Cajal (ES)
Good health and well-being
Openalex Percentile: Top 24%
Bladder and Urothelial Cancer Treatments
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