Front Cover: Impact of Docking Strand Design on Spatial Resolution in DNA‐Points Accumulation for Imaging in Nanoscale Topography (ChemPhysChem 5/2026)
The Front Cover shows how DNA—PAINT docking strand architecture influences nanoscale image quality. Short single—motif docking strands keep localizations tightly clustered around trimeric PCNA, thus enabling precise molecular detail. In contrast, extended multivalent sequences expand the accessible volume, causing broader, less accurate patterns and reflecting the balance between imaging speed and structural accuracy. More information can be found in the Research Article by D. Helmerich, G. Beliu, and co-workers (DOI: 10.1002/cphc.202500803). Image created in BioRender: Helmerich, D. (2026) https://BioRender.com/3plpbtv.
Authors
- Patrick Eiring
- Gerti Beliu
- Dominic A. Helmerich
- Markus Sauer
- Sören Doose
- Made Budiarta
Institutions
- University of Würzburg (DE)
- University of Regensburg (DE)
Publication Details
- Journal
- ChemPhysChem
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1002/cphc.70351
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00