Front Cover: Impact of Docking Strand Design on Spatial Resolution in DNA‐Points Accumulation for Imaging in Nanoscale Topography (ChemPhysChem 5/2026)

The Front Cover shows how DNA—PAINT docking strand architecture influences nanoscale image quality. Short single—motif docking strands keep localizations tightly clustered around trimeric PCNA, thus enabling precise molecular detail. In contrast, extended multivalent sequences expand the accessible volume, causing broader, less accurate patterns and reflecting the balance between imaging speed and structural accuracy. More information can be found in the Research Article by D. Helmerich, G. Beliu, and co-workers (DOI: 10.1002/cphc.202500803). Image created in BioRender: Helmerich, D. (2026) https://BioRender.com/3plpbtv.

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Publication Details

Journal
ChemPhysChem
Published
2026-03-13
DOI
https://doi.org/10.1002/cphc.70351
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
Field-Weighted Citation Impact
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article

Front Cover: Impact of Docking Strand Design on Spatial Resolution in DNA‐Points Accumulation for Imaging in Nanoscale Topography (ChemPhysChem 5/2026)

Patrick Eiring, Gerti Beliu, Dominic A. Helmerich, Markus Sauer et al.
ChemPhysChem
Advanced Fluorescence Microscopy Techniques
article

Front Cover: Impact of Docking Strand Design on Spatial Resolution in DNA‐Points Accumulation for Imaging in Nanoscale Topography (ChemPhysChem 5/2026)

Patrick Eiring, Gerti Beliu, Dominic A. Helmerich, Markus Sauer, Sören Doose, Made Budiarta
article en

Abstract

The Front Cover shows how DNA—PAINT docking strand architecture influences nanoscale image quality. Short single—motif docking strands keep localizations tightly clustered around trimeric PCNA, thus enabling precise molecular detail. In contrast, extended multivalent sequences expand the accessible volume, causing broader, less accurate patterns and reflecting the balance between imaging speed and structural accuracy. More information can be found in the Research Article by D. Helmerich, G. Beliu, and co-workers (DOI: 10.1002/cphc.202500803). Image created in BioRender: Helmerich, D. (2026) https://BioRender.com/3plpbtv.

ChemPhysChemVol. 27(5)
University of Würzburg (DE), University of Regensburg (DE)
Openalex Percentile: Top 21%
Advanced Fluorescence Microscopy Techniques
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