Use of Oral Metformin Therapy for Therapy‐Induced Hyperglycemia in Pediatric Patients With Acute Lymphoblastic Leukemia

Oral metformin proved to be a safe and effective first-line option for managing TIH in pediatric ALL. Insulin therapy could be avoided in majority of the patients (73.4% in induction, 68.1% in re-induction), making this drug an attractive first-line option for children with treatment-induced non-severe hyperglycemia.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-03-13
DOI
https://doi.org/10.1002/1545-5017.70185
Primary Topic
Childhood Cancer Survivors' Quality of Life
Type
article
Field-Weighted Citation Impact
0.00
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article

Use of Oral Metformin Therapy for Therapy‐Induced Hyperglycemia in Pediatric Patients With Acute Lymphoblastic Leukemia

Archana Arya, Ankita Chakraborty, Anupam Sachdeva, Manas Kalra
Pediatric Blood & Cancer
Childhood Cancer Survivors' Quality of Life
article

Use of Oral Metformin Therapy for Therapy‐Induced Hyperglycemia in Pediatric Patients With Acute Lymphoblastic Leukemia

Archana Arya, Ankita Chakraborty, Anupam Sachdeva, Manas Kalra
article en

Abstract

Oral metformin proved to be a safe and effective first-line option for managing TIH in pediatric ALL. Insulin therapy could be avoided in majority of the patients (73.4% in induction, 68.1% in re-induction), making this drug an attractive first-line option for children with treatment-induced non-severe hyperglycemia.

Pediatric Blood & Cancer
Sir Ganga Ram Hospital (IN)
Good health and well-being
Openalex Percentile: Top 23%
Childhood Cancer Survivors' Quality of Life
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