Acute myocarditis and rhabdomyositis after coronavirus disease 2019 messenger RNA vaccination and intensive training: a case report

We suggest that strenuous training associated with skeletal muscle damage, together with the strong immunostimulatory effect of messenger RNA vaccination, may lead to autoimmune rhabdomyositis that potentially cross-reacts with the myocardium. Athletes should be aware of the potential danger of heavy training in close proximity to vaccination or acute infections.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-03-13
DOI
https://doi.org/10.1186/s13256-026-05948-6
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Acute myocarditis and rhabdomyositis after coronavirus disease 2019 messenger RNA vaccination and intensive training: a case report

Jieyu Wu, Béla Bozóky, László Székely, Attila Szakos
Journal of Medical Case Reports
Inflammatory Myopathies and Dermatomyositis
article

Acute myocarditis and rhabdomyositis after coronavirus disease 2019 messenger RNA vaccination and intensive training: a case report

Jieyu Wu, Béla Bozóky, László Székely, Attila Szakos
article en

Abstract

We suggest that strenuous training associated with skeletal muscle damage, together with the strong immunostimulatory effect of messenger RNA vaccination, may lead to autoimmune rhabdomyositis that potentially cross-reacts with the myocardium. Athletes should be aware of the potential danger of heavy training in close proximity to vaccination or acute infections.

Journal of Medical Case Reports
Karolinska University Hospital (SE), Karolinska Institutet (SE), First Affiliated Hospital of Guangzhou Medical University (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 26%
Inflammatory Myopathies and Dermatomyositis
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