Biochemical, molecular, and in silico insights into the effects of cyphenothrin on Culex quinquefasciatus mosquitoes

These findings suggest the involvement of a few detoxifying genes in resistance development against cyphenothrin in Cx. quinquefasciatus mosquitoes and advocates the urgent need for regular resistance monitoring, molecular surveillance, gene knockdown studies, and incorporation of synergists into integrated vector management frameworks to sustain effectiveness of mosquito control programs.