Average alcohol consumption among patients diagnosed with liver cirrhosis: A cross-sectional analysis
Background : Alcohol-related liver cirrhosis is a leading cause of chronic liver disease worldwide. Risk and progression are dose-dependent and influenced by exposure duration and sex-specific susceptibility. Aim : To evaluate the quantity and duration of alcohol consumption in patients with alcohol-related liver cirrhosis. Materials and methods : In this prospective cross-sectional study (January 2022–December 2025), 548 adults with alcohol-related cirrhosis (Child–Pugh classes A–C) hospitalized at the University Emergency Hospital “Pirogov,” Sofia, were included. Alcohol intake was self-reported and converted to grams of pure ethanol per week. Results : The mean weekly intake was 339.66 g of ethanol (28.3 standard drinks). The mean duration of consumption before diagnosis was 107.72 ± 28.84 months. Alcohol intake differed significantly across Child–Pugh classes ( F = 6.62, p < 0.001), with the highest consumption in Child C. Duration of intake was also significantly associated with quantity consumed ( p < 0.001). Conclusion : Patients with alcohol-related cirrhosis demonstrate sustained high alcohol intake over prolonged periods. Greater consumption and longer exposure are significantly associated with more severe hepatic impairment.
Authors
- Niya Emilova Semerdzhieva (ORCID: https://orcid.org/0000-0003-1878-9807)
- D. Genov
- Yozlem Ali Kobakova
- Maria Becheva (ORCID: https://orcid.org/0000-0002-2734-8280)
- Maria Chaneva
- Maria Moneva-Sakelarieva
- Stefka Ivanova (ORCID: https://orcid.org/0000-0003-3324-5840)
- Kiril Atliev
- Angelina Kirkova-Bogdanova
- Ventseslava Petrova Atanasova
- Nikolay Zarkov Bashev (ORCID: https://orcid.org/0009-0007-8029-9856)
- Radoslav Fedeev Todorov
- Ismail Elhanov Bashov
- Yonko Tsvetanov Yonchev
- Dariya Lyubomirova Todorova
- Vasil Sotirov Kyosev
- Kamen Valentinov Danov
- Danka Petrova Obreshkova
- Petar Yordanov Atanasov
Institutions
- Medical University Plovdiv (BG)
- Medical University of Sofia (BG)
- National Institute of Emergency Medicine "Pirogov" (BG)
- University Hospital St. Ivan Rilski (BG)
- University Hospital Dr. Georgi Stranski (BG)
- Military Medical Academy (BG)
- University Multipurpose Hospital for Active Treatment "Sveti Georgi" (BG)
Publication Details
- Journal
- Pharmacia
- Published
- 2026-03-13
- DOI
- https://doi.org/10.3897/pharmacia.73.e189496
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00