Relapse of adult B-cell acute lymphoblastic leukemia in the bilateral lacrimal glands: A case report and literature review

Bilateral lacrimal gland enlargement in patients with a history of ALL may represent isolated extramedullary relapse, even in the absence of hematologic abnormalities. Early histopathologic confirmation is essential to prevent diagnostic delay and to enable timely systemic management in ALL patients.

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Journal
Medicine
Published
2026-03-13
DOI
https://doi.org/10.1097/md.0000000000048025
Primary Topic
Nasolacrimal Duct Obstruction Treatments
Type
article
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0.00
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article

Relapse of adult B-cell acute lymphoblastic leukemia in the bilateral lacrimal glands: A case report and literature review

Kyung Chul Yoon, Hyo Ju Jang, Ga-Young Song, Hyeon-Jeong Yoon et al.
Medicine
Nasolacrimal Duct Obstruction Treatments
article

Relapse of adult B-cell acute lymphoblastic leukemia in the bilateral lacrimal glands: A case report and literature review

Kyung Chul Yoon, Hyo Ju Jang, Ga-Young Song, Hyeon-Jeong Yoon, Sung Sun Kim
article en

Abstract

Bilateral lacrimal gland enlargement in patients with a history of ALL may represent isolated extramedullary relapse, even in the absence of hematologic abnormalities. Early histopathologic confirmation is essential to prevent diagnostic delay and to enable timely systemic management in ALL patients.

MedicineVol. 105(11)
Chonnam National University Hospital (KR), Chonnam National University Hwasun Hospital (KR)
Good health and well-being
Openalex Percentile: Top 23%
Nasolacrimal Duct Obstruction Treatments
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