New Delhi Metallo-β-Lactamase Carbapenem-Resistant <i>Klebsiella pneumoniae</i> in Neonates: A Genome-Based Surveillance Study
This study suggests clonal dissemination of CRKP in neonates and documents a shift in the predominant ST from ST789 to ST35. ST35 strains displayed distinct resistance phenotypes and siderophore-linked virulence genes. Given that CRKP represented 73 of 310 (23.5%) neonatal K. pneumoniae isolates during 2018-2024, these data underscore the need for sustained surveillance and strengthened infection control measures in neonatal care units.
Authors
- Jiaji Ling
- Yongmei Jiang
- Liting Liang
- Qi Zhang (ORCID: https://orcid.org/0000-0001-9259-486X)
- Wenjing Wu
- Xingxin Liu (ORCID: https://orcid.org/0009-0005-7327-8470)
- Yu Feng
- Wei Zhou
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-01-13
- DOI
- https://doi.org/10.1093/infdis/jiag034
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00