Disruption of primary ciliary prostaglandin E2 signaling by transforming growth factor-β1 impairs endometrial receptivity
Endometrial primary cilia are indispensable for decidualization and are potential biomarkers for predicting endometrial receptivity. Targeting TGF-β signaling to restore ciliated cell number and ciliary length may serve as a potential therapeutic strategy to improve fertility outcomes.
Authors
- Chia‐Yih Wang (ORCID: https://orcid.org/0000-0002-9196-0802)
- Po-Fan Chen (ORCID: https://orcid.org/0000-0003-0760-0482)
- C. L. Lee
- S. Tsai
- Wan-Ning Li (ORCID: https://orcid.org/0000-0002-2057-885X)
- Ching‐Chun Lin (ORCID: https://orcid.org/0000-0003-1059-1038)
- Ting-Chien Lin
- Huan-Tzu Hou (ORCID: https://orcid.org/0000-0003-1069-1776)
- Po-Hung Pan
- Meng-Hsing Wu
- Yi-Chen Chen
Institutions
- National Chung Cheng University (TW)
- National Cheng Kung University Hospital (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2026-03-11
- DOI
- https://doi.org/10.1186/s12929-026-01233-2
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00