Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

These data provide a rationale for the combination of lenalidomide with IL-2 family of cytokines to enhance the effectiveness of NK cells.

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Publication Details

Journal
PLoS ONE
Published
2026-03-12
DOI
https://doi.org/10.1371/journal.pone.0344471
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

Nicole Fortenbery, Alexandra Calescibetta, Erika Adriana Eksioglu, Kenneth L. Wright et al.
PLoS ONE
Immune Cell Function and Interaction
article

Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

Nicole Fortenbery, Alexandra Calescibetta, Erika Adriana Eksioglu, Kenneth L. Wright, Thu Le Trinh, Nhan Tu, Sean Christiansen, Grace Ward, Tiffany N. Razabdouski, Pingyan Cheng, Sheng Wei, Xianghong Chen, Robert Dalton, Jinghong Liu, Annelise J. Glode
article en

Abstract

These data provide a rationale for the combination of lenalidomide with IL-2 family of cytokines to enhance the effectiveness of NK cells.

PLoS ONEVol. 21(3)
Moffitt Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 23%
Immune Cell Function and Interaction
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