Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies
Our findings indicate that circulating plasma elastase could be useful to distinguish across diseases in the differential diagnosis of hematological malignancies, and could be used as additional prognostic biomarker of disease progression and responsiveness to therapies.
Authors
- Francesca Picone (ORCID: https://orcid.org/0009-0009-6509-9789)
- Carmine Selleri (ORCID: https://orcid.org/0000-0002-5861-8984)
- Marisa Gorrese (ORCID: https://orcid.org/0000-0002-4603-712X)
- Valentina Giudice (ORCID: https://orcid.org/0000-0002-7492-6848)
- Luca Pezzullo (ORCID: https://orcid.org/0000-0001-6867-7331)
- Pasqualina Scala (ORCID: https://orcid.org/0000-0001-6292-4186)
- Anna Maria Della Corte (ORCID: https://orcid.org/0009-0000-1972-6336)
- Denise Morini (ORCID: https://orcid.org/0009-0005-4921-1081)
- Bianca Cuffa
- Laura Mettivier (ORCID: https://orcid.org/0000-0003-1473-7487)
- Bianca Serio (ORCID: https://orcid.org/0000-0001-6613-2370)
- Danilo De Novellis (ORCID: https://orcid.org/0000-0002-2590-0529)
- Maria Carmen Martorelli
- Matteo D'Addona
- Angela Bertolini
Institutions
- University of Salerno (IT)
- Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona (IT)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1111/ijlh.70090
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00