A systematic review of dengue controlled human infection studies: safety, viral kinetics and immunology
DCHIMs of primary dengue are a valuable and safe tool that has supported vaccine development. Further work is needed to expand DCHIMs to endemic settings and as a model of secondary dengue.
Authors
- Srishti Chhabra (ORCID: https://orcid.org/0000-0001-8050-9357)
- Po Ying Chia
- Yee-Sin Leo
- Barnaby Edward Young
Institutions
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Tan Tock Seng Hospital (SG)
- National University Health System (SG)
- National Centre for Infectious Diseases (SG)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1371/journal.pntd.0014086
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 41.85